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Optimization of Perioperative Approaches for Advanced and Late Stages of Gastric Cancer: Clinical Proposal Based on Literature Evidence, Personal Experience, and Ongoing Trials and Research by Beeharry, Maneesh Kumarsing; Zhang, Tian Qi; Liu, Wen Tao; Gang, Zhu Zheng is a Medicine article available to read on EtoBox.
What is Optimization of Perioperative Approaches for Advanced and Late Stages of Gastric Cancer: Clinical Proposal Based on Literature Evidence, Personal Experience, and Ongoing Trials and Research about?
## Background The high incidence of gastric cancer (GC) and paradoxical high prevalence of advanced stage GC, amounting to around 2/3 at time of diagnosis, have urged doctors and researchers around the world not only to ameliorate the detection rate of GC at early stages but also to optimize the clinical management of GC at advanced stages. ## Content We hereby recommend a more goal-oriented multimodality approach with objectives to increase survival rate and improve survival status. Based on precision and accurate clinical staging at diagnosis, we suggest that advanced stage GC (AGC) patients should be channeled into different treatment plans according to their disease status where they can be subjected to comprehensive measures involving chemo, radio, immunological, or target therapies depending on the pathophysiological behavior of their tumor. Patients assessed as potentially resectable cT4N + M0 can undergo neoadjuvant chemotherapy with intent of tumor downsizing and downgrading followed by surgery with intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) to decrease the incidence of peritoneal dissemination due to surgical trauma and adjuvant chemotherapy and radi
Who reads Optimization of Perioperative Approaches for Advanced and Late Stages of Gastric Cancer: Clinical Proposal Based on Literature Evidence, Personal Experience, and Ongoing Trials and Research?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Beeharry, Maneesh Kumarsing; Zhang, Tian Qi; Liu, Wen Tao; Gang, Zhu Zheng
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2003-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1477-7819)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)