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Longitudinal Quantification of Growth and Changes in Primary Tracheobronchomalacia Sites in Children by Ian B. Masters; Paul V. Zimmerman; Anne B. Chang is a Medicine article available to read on EtoBox.

What is Longitudinal Quantification of Growth and Changes in Primary Tracheobronchomalacia Sites in Children about?

## Abstract ## Rationale Longitudinal follow‐up of children with tracheobronchomalacia is essential to improving our understanding of these disorders, yet currently, there is no such data. ## Objectives To longitudinally define malacia sites and quantify the cross‐sectional area (CSA) of the lumen using a bronchoscopic technique and to relate these measurements to illness profiles. ## Methods The validated color histogram mode technique was utilized to quantify primary malacia lesions and airway sites' CSA. Illness frequency, validated scales of illness and cough diary scores were prospectively used to assess clinical profiles. ## Results Thirty‐five malacia sites were defined from the 2 studies of 21 children. CSA of 21 (60%) of the malacia lesions increased, 5 (14%) new lesions appeared, 5 (14%) decreased in size, 3 (8%) remained unchanged, and 1(3%) was indeterminate. Overall there was no statistically significant change in paired‐data assessments of malacia sites' area while there was a significant increase in area of non‐malacia sites. The median yearly growth rate for the malacia sites and non‐malacia was 3.65 mm^2^/year sites and 5.38 mm^2^/year, respectively (__P__ = 0.31).

Who reads Longitudinal Quantification of Growth and Changes in Primary Tracheobronchomalacia Sites in Children?

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Author
Ian B. Masters; Paul V. Zimmerman; Anne B. Chang
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-6863)
Published
2007
Language
EN
Field
Medicine (Health Sciences)

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