Can I read Some Pharmaceutical Drugs (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans, 66) on EtoBox?

Some Pharmaceutical Drugs (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans, 66) by International Agency for Research on Cancer; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; Kongress is a book available to read on EtoBox.

What is Some Pharmaceutical Drugs (IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans, 66) about?

<p>Evaluates the carcinogenic risk to humans posed by the therapeutic use of thirteen pharmaceutical drugs, including eight benzodiazepines and related compounds used for the treatment of anxiety and as sedatives and anticonvulsants, three triphenylethylene anti-oestrogenic compounds developed for the treatment of breast cancer, and two cholesterol-lowering agents used to treat patients at high risk for cardiovascular disease. Evaluations are based on a critical assessment of all data available for these compounds, including abundant information on pharmacokinetic and pharmacodynamic effects, precise studies of exposure-response relationships, and findings that shed light on mechanisms of carcinogenic action. <br>The most extensive monograph evaluates the large body of data on tamoxifen, which has been used for almost two decades as the first-line endocrine therapy for postmenopausal women with advanced metastatic breast cancer. Tamoxifen is also used as adjuvant therapy in patients with breast cancer and is being tested for use as a preventive agent. The evaluation found sufficient evidence in humans for the carcinogenicity of tamoxifen in increasing the risk for endometrial cance

Author

International Agency for Research on Cancer; IARC Working Group on the Evaluation of Carcinogenic Risks to Humans; Kongress

Publisher

[Lyon]: World Health Organization, International Agency for Research on Cancer

Published

1996

Language

EN

ISBN

9789283212669

Subjects

Medical, Mathematics, Nursing