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Maternal vitamin D deficiency in early pregnancy and perinatal and long-term outcomes by Soo Bin Lee; Sang Hee Jung; Hanna Lee; Sae Mi Lee; Jae Eun Jung; Nari Kim; Ji Yeon Lee is a Medicine article available to read on EtoBox.

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## Background Vitamin D deficiency is common in pregnant women. Some studies have linked vitamin D deficiency to obstetric complications such as gestational hypertension, gestational diabetes, and preterm birth. Therefore, the objective of this study is to investigate the potential impact of vitamin D deficiency during pregnancy on both perinatal and long-term outcomes. ## Methods In this retrospective study, conducted between 2017 and 2021, we analyzed the data of 1079 singleton pregnant women with no medical or surgical complications prior to pregnancy. We evaluated obstetric and perinatal outcomes, as well as neurodevelopmental outcomes using Bayley-III tests, Gross Motor Function Measure, or chart review. ## Results The maternal serum vitamin D level in the first trimester was 18.2 ± 9.0 ng/mL. Vitamin D deficiency (<20 ng/mL) was found in 308 (62.0%) women in the first trimester, of which 288 women (26.7%) were in the very deficient group (<10 ng/mL). There were no differences in maternal age, body mass index, and previous preterm birth between the group with vitamin D < 10 ng/mL and ≥10 ng/mL group. There were also no differences in the rates of gestational hypertension, gest

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Author

Soo Bin Lee; Sang Hee Jung; Hanna Lee; Sae Mi Lee; Jae Eun Jung; Nari Kim; Ji Yeon Lee

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Physical Sciences)