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Cancer Evolution: Hypoxia & Acidity Effects by vikasravidas789 is a document available to read on EtoBox.
This study presents a mathematical model examining how hypoxia and acidity influence the evolutionary dynamics of cancer cells in vascularized tumors. The model, formulated as a system of partial integro-differential equations, simulates the adaptation of tumor cells to varying concentrations of oxygen, glucose, and lactate, revealing the emergence of intra-tumor phenotypic heterogeneity. The findings suggest that the order of resistance to hypoxia and acidity in tumors is influenced by the interactions bet
- Author
- vikasravidas789
- Language
- EN