Opening book details…
Can I read Age-associated Thin Hair Displays Molecular, Structural and Mechanical Characteristic Changes on EtoBox?
Age-associated Thin Hair Displays Molecular, Structural and Mechanical Characteristic Changes by Frédéric Baltenneck; Gaianne Genty; Elias Bou Samra; Marina Richena; Duane P. Harland; Stefan Clerens; Emilie Leccia; Mickael Le Balch; Jean Doucet; Jean-François Michelet; Stéphane Commo is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Age-associated Thin Hair Displays Molecular, Structural and Mechanical Characteristic Changes about?
Hair thinning occurs during normal chronological aging in women and in men leading to an increased level of thinner hair shafts alongside original thicker shafts. However, the characteristics of age-associated thin hairs remain largely unknown. Here we analyzed these characteristics by comparing at multiscale thin and thick hairs originated from Caucasian women older than 50 years. We observed that the cortex of thick hair contains many K35(+)/K38(-) keratinocytes that decrease in number with decreasing hair diameter. Accordingly, X-ray diffraction revealed differences supporting that thin and thick hairs are different with regards to the nature of the intermediate filaments making up their cortices. In addition, we observed a direct correlation between hair ellipticity and diameter with thin hairs having an unexpected round shape compared to the elliptic shape of thick hairs. We also observed fewer cuticle layers and a reduced frequency of a medullae in thin hairs. Regarding mechanical properties, thin hairs exhibited a surprising increased rigidity, a decrease of the viscosity and a decrease of the water diffusion coefficient. Hence, aged-associated thin hairs exhibit numerous mo
Who reads Age-associated Thin Hair Displays Molecular, Structural and Mechanical Characteristic Changes?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Frédéric Baltenneck; Gaianne Genty; Elias Bou Samra; Marina Richena; Duane P. Harland; Stefan Clerens; Emilie Leccia; Mickael Le Balch; Jean Doucet; Jean-François Michelet; Stéphane Commo
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)