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Amphotericin B Administration Guidelines by Echa Alifyanty Syarif is a document available to read on EtoBox.

Amphotericin B is an antifungal agent produced by Streptomyces species. It is a yellow to orange powder that is soluble in acidic or basic water and other solvents like DMF and DMSO. It works by binding to ergosterol in the fungal cell membrane, disrupting permeability. Common side effects include fever, chills, nausea, and nephrotoxicity. Guidelines recommend administering it over 4-6 hours at rates less than 0.08 mg/kg/hr along with saline to reduce toxicity risks.

Author

Echa Alifyanty Syarif

Language

EN