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Physiology of Glucose Homeostasis by Shanta J. Persaud; Peter M. Jones is a book available to read on EtoBox.

What is Physiology of Glucose Homeostasis about?

This chapter provides an overview of the physiological mechanisms underlying appropriate control of blood glucose levels. In particular, it focuses on the anatomy and cellular composition of islets of Langerhans; regulation of synthesis and storage of the anabolic hormone insulin in secretory granules of islet beta-cells; cellular mechanisms by which elevations in blood glucose levels stimulate insulin release from beta-cells by a process known as exocytosis; modulation of glucose-stimulated insulin secretion by hormones and neurotransmitters; and the physiological signal transduction pathways used by insulin to stimulate storage of fuels in adipose tissue, liver, and skeletal muscle. It also reviews the deleterious effects of chronic hyperglycaemia that are responsible for diabetic complications.

Author

Shanta J. Persaud; Peter M. Jones

Publisher

Oxford University Press

Published

2021

Language

EN