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What is Leukocoria in Retinoblastoma Diagnosis about?
Retinoblastoma is the most common intraocular malignancy in children, typically diagnosed by age three, with leukocoria being the most common presenting sign. It can be unilateral or bilateral, with a significant genetic component linked to mutations in the RB1 gene, and treatment often involves chemotherapy and focal therapies. The prognosis is generally favorable in resource-rich countries, with a 10-year survival rate of 99%, but poorer outcomes are observed in resource-poor settings.
- Author
- Shen
- Language
- EN