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What is DREADD Ligands and Applications Guide about?

Designer Receptors Exclusively Activated by Designer Drugs (DREADD) are engineered G protein-coupled receptors that can be specifically activated by otherwise inert small molecules to remotely and non-invasively control cellular signaling. These receptors are generally unresponsive to endogenous ligands, allowing discrete control of cellular activity with limited off-target effects. DREADDs enable investigation of relationships between particular cells and behaviors.

Author

vasiliy

Language

EN