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Depressive symptoms in patients with Alzheimer's disease by Nitin Purandare; Alistair Burns; Sarah Craig; Brian Faragher; Kathy Scott is a Medicine article available to read on EtoBox.

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## Abstract ## Objectives A comparison was made between the depressive symptom profiles of thirty patients with Alzheimer's disease (AD) who did not have co‐existing depression and thirty patients with major depression who did not have co‐existing dementia. The main objective was to identify symptoms common to both disorders and those which may be able to differentiate AD from major depression. ## Method A sample of patients suffering from either AD (__n__ = 30) or major depression (__n__ = 30) were recruited from a specialist old age psychiatry service. Depressive symptoms were profiled using the Hamilton Depression Rating Scale (HDRS), the Cornell Scale for Depression in Dementia (CSDD) and the Geriatric Depression Scale (GDS). ## Results Depressive symptoms were present in AD in the absence of coexistent major depression. Certain depressive symptoms from all the three scales such as sadness, diurnal variation in mood and early or late insomnia were able to differentiate the two disorders with almost 90% accuracy while symptoms such as irritability, retardation and weight loss were common to both and were unable to differentiate the two. ## Conclusion Depressive symptoms occur in

Who reads Depressive symptoms in patients with Alzheimer's disease?

Author

Nitin Purandare; Alistair Burns; Sarah Craig; Brian Faragher; Kathy Scott

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0885-6230)

Published

2001

Language

EN

Field

Medicine (Health Sciences)