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Can I read Influence of First-pass Effect on Recanalization Outcomes in the Era of Mechanical Thrombectomy: a Systemic Review and Meta-analysis on EtoBox?
Influence of First-pass Effect on Recanalization Outcomes in the Era of Mechanical Thrombectomy: a Systemic Review and Meta-analysis by Xuesong Bai; Xiao Zhang; Wuyang Yang; Yinhang Zhang; Tao Wang; Ran Xu; Yan Wang; Long Li; Yao Feng; Kun Yang; Xue Wang; Haiqing Song; Qingfeng Ma; Liqun Jiao is a Medicine article available to read on EtoBox.
What is Influence of First-pass Effect on Recanalization Outcomes in the Era of Mechanical Thrombectomy: a Systemic Review and Meta-analysis about?
## Purpose: This systematic review and meta-analysis summarized the current literature to compare the safety and efficacy between first-pass effect (fpe) and multiple-pass effect (mpe) for thrombectomy in treatment of acute ischemic stroke (ais). ## Methods: Major databases were searched for studies which reported clinical outcomes regarding successful or complete recanalization after first pass of mechanical thrombectomy in ais. the assessment of bias was performed using different scales. i statistic was used to evaluate heterogeneity between reviewers. subgroup, meta-regression, and sensitivity analyses were conducted to explore the source of heterogeneity. visualization of funnel plots was used to evaluate publication bias. ## Results: A total of 9 studies were eligible for final analysis. for successful recanalization (mtici 2b-3), favorable outcomes were seen in 49.7% (95% confidence interval (ci): 40.5-58.9%) and 34.7% (95% ci: 26.8-42.7%) of fpe and mpe patients, respectively. mortality at 3 months was 13.8% (95% ci: 10.8-16.9%) and 26.0% (95% ci: 17.7-34.2%), respectively. for complete recanalization (mtici 2c-3), proportion of favorable outcomes were 62.7% (95% ci: 51.2-74
Who reads Influence of First-pass Effect on Recanalization Outcomes in the Era of Mechanical Thrombectomy: a Systemic Review and Meta-analysis?
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- Author
- Xuesong Bai; Xiao Zhang; Wuyang Yang; Yinhang Zhang; Tao Wang; Ran Xu; Yan Wang; Long Li; Yao Feng; Kun Yang; Xue Wang; Haiqing Song; Qingfeng Ma; Liqun Jiao
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0028-3940)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)