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What is Iscience about?

The study investigates the protein interactomes of six schizophrenia risk genes in human neurons to better understand their roles in neurodevelopmental disorders. The resulting protein network is enriched for common variant risk across different ancestries and aids in prioritizing genes in GWAS loci. Findings highlight the importance of brain cell-type-specific interactomes in interpreting genetic signals related to schizophrenia and related conditions.

Author

hellochloe0508

Language

EN