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What is Kumis Kucing Leaves: SLN Formulation & α-Glucosidase Inhibition about?

1) The study aimed to formulate solid lipid nanoparticles (SLN) from the 70% ethanol extract of kumis kucing (Orthosiphon stamineus) leaves and test their ability to inhibit the alpha-glucosidase enzyme. 2) Three SLN formulas were produced with varying concentrations of tween 80 and propylene glycol. Formula I had particle sizes around 51.6 nm and zeta potential of -27.67. 3) All extract and SLN formulas showed alpha-glucosidase enzyme inhibitory activity, with IC50 values around 130-132 ppm, similar to

Author

Rita Rakhma

Language

EN