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Antioxidant and Antiproliferative Activities of Several Garlic Forms by Farhat, Zeinab (author);Scheving, Tyler (author);Aga, Diana S. (author);Hershberger, Pamela A. (author);Freudenheim, Jo L. (author);Hageman Blair, Rachael (author);Mammen, Manoj J. (author);Mu, Lina (author) is a Medicine article available to read on EtoBox.
What is Antioxidant and Antiproliferative Activities of Several Garlic Forms about?
It is hypothesized that garlic, Allium sativum, might protect against oxidative stress that causes damage to cells and tissues leading to the development of various health conditions including cancer. However, it is not known whether garlic’s potential anticancer benefits differ by form of garlic consumed. This study aimed to quantify and compare the in vitro antioxidant and antiproliferative activity of several garlic forms in water and alcohol extracts including fresh garlic, fresh garlic set aside, heated garlic, heated garlic set aside, garlic powder, black garlic, two commercially available garlic supplements. Antioxidant activity of different garlic forms were measured using three assays: DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) assay, superoxide assay, and hydroxyl assay. In vitro effects of garlic extracts were investigated against the most common lung cancer subtypes: H520, H1975, and A549 cell lines using the sulforhodamine B (SRB) assay. Among free radical scavenging assays, Garlicin®, a commercially available supplement, displayed high antioxidant activity in water and alcohol extracts (DPPH assay: 2.02 mg AAE (mg ascorbic acid equivalent)/g garlic and 3.53 mg AAE/
Who reads Antioxidant and Antiproliferative Activities of Several Garlic Forms?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Farhat, Zeinab (author);Scheving, Tyler (author);Aga, Diana S. (author);Hershberger, Pamela A. (author);Freudenheim, Jo L. (author);Hageman Blair, Rachael (author);Mammen, Manoj J. (author);Mu, Lina (author)
- Publisher
- MDPI AG
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)