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What is Virulence of Sporothrix Species in Mice about?

This study compared the virulence of five Sporothrix species (S. albicans, S. brasiliensis, S. globosa, S. mexicana, and S. schenckii) in a murine model using two strains of each species. Mice were inoculated intravenously with either 2x107 or 2x104 conidia. Only S. brasiliensis at the lower inoculum and S. brasiliensis and S. schenckii at the higher inoculum caused mortality in mice. Tissue burden and histopathological studies showed S. brasiliensis had the highest fungal load and lesions in organs, while

Author

Dany Corrêa

Language

EN