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The commentary discusses UniFrac, a beta-diversity measure that utilizes phylogenetic information to compare microbial communities, and its effectiveness in multivariate statistical analyses. Despite criticisms regarding its suitability as a distance metric, the authors provide mathematical proof of its validity and emphasize the importance of considering sampling depth when interpreting UniFrac values. They recommend using jackknifing techniques to mitigate the effects of sampling variability and support t

Author

vanishivshetty

Language

EN