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Low predictive accuracy of the Kattan postoperative nomogram for renal cell carcinoma recurrence in a population of French patients by Vincent Hupertan; Morgan Roupret; Jean-Francois Poisson; Yves Chretien; Bertrand Dufour; Nicolas Thiounn; Arnaud Mejean is a Medicine article available to read on EtoBox.

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## Abstract ## BACKGROUND. The aim of the current study was to establish the predictive accuracy of the Kattan postoperative nomogram for nonmetastatic renal cell carcinoma (RCC) by comparing predictions with actual disease recurrence in patients who underwent surgery in a single center in France. ## METHODS. Between 1985 and 2000, 844 patients were treated for RCC. The following data were collated: age, symptoms, histology, tumor size, grade, TNM 1997 stage, recurrence, and progression. For each patient a prognostic score (predicted probability) for recurrence‐free survival (RFS) at 5 years was calculated using the Kattan nomogram. The discriminating ability of the model was assessed by Harrell's concordance index (__c__‐index). Bootstrapping was used to assess confidence intervals. Furthermore, survival was then estimated by the Kaplan‐Meier method and Cox proportional hazards regression analysis. ## RESULTS. In all, 565 patients (median age, 62 years) were included. At the time of the last follow‐up, 81 patients had died and 101 had experienced RCC recurrence. The __c__‐index for RFS (Kattan nomogram) was only 0.607 (95% confidence interval [CI]: 0.576–0.635). The 5‐year RFS rat

Who reads Low predictive accuracy of the Kattan postoperative nomogram for renal cell carcinoma recurrence in a population of French patients?

Author

Vincent Hupertan; Morgan Roupret; Jean-Francois Poisson; Yves Chretien; Bertrand Dufour; Nicolas Thiounn; Arnaud Mejean

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

2006

Language

EN

Field

Medicine (Health Sciences)