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Can I read Kinetics of denaturation of DNA on EtoBox?
Kinetics of denaturation of DNA by Harold R. Massie; Bruno H. Zimm is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Kinetics of denaturation of DNA about?
The kinetica of denaturation of DNA have been studied by relaxation techniques. Examination of the terminal relaxation times for a variety of DNA's under a variety of conditions has shown that DNA denaturation is principally a hydrodynamically limited p r m . Measurements within the heli-coil transition have demonstrated that the experimentally measured terminal relaxation times are a function of the following: (1) position in the helix-coil transition; (2) ionic strength of the solvent; (3) solvent viscosity; (4) DNA concentration; (5) molecular weight; (6) number and position of single-strand breaks. The dependence of the terminal relaxation time on the above mentioned factors can be attributed to hydrodynamic effects. Thus a hydrodynamic model for DNA unwinding is required. The model which best fits the data involves the assumption of a rotational frictional coefficient independent of molecular weight. This assumption is suggested by the fact that the relaxation time is proportional to the first power of the molecular weight.
Who reads Kinetics of denaturation of DNA?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Harold R. Massie; Bruno H. Zimm
- Publisher
- Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0006-3525)
- Published
- 1969
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)