Can I read The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities on EtoBox?

The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities by Zilong Zhang; Yu Sun; Yiming Li; Xiaomei Song; Rui Wang; Dongdong Zhang is a Chemistry article available to read on EtoBox.

What is The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities about?

Marine-derived piperazine alkaloids (MDPAs) constitute a significant group of natural compounds known for their diverse structures and biological activities. Over the past five decades, substantial efforts have been devoted to isolating these alkaloids from marine sources and characterizing their chemical and bioactive profiles. To date, a total of 922 marine-derived piperazine alkaloids have been reported from various marine organisms. These compounds demonstrate a wide range of pharmacological properties, including cytotoxicity, antibacterial, antifungal, antiviral, and various other activities. Notably, among these activities, cytotoxicity emerges as the most prominent characteristic of marine-derived piperazine alkaloids. This review also summarizes the structureactivity relationship (SAR) studies associated with the cytotoxicity of these compounds. In summary, our objective is to provide an overview of the research progress concerning marine-derived piperazine alkaloids, with the aim of fostering their continued development and utilization.

Who reads The potential of marine-derived piperazine alkaloids: Sources, structures and bioactivities?

Author

Zilong Zhang; Yu Sun; Yiming Li; Xiaomei Song; Rui Wang; Dongdong Zhang

Publisher

Elsevier BV

Published

2024

Language

EN

Field

Chemistry (Physical Sciences)