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New benzoquinone pigments from the hydnoid fungus Sarcodontia setosa and their biosynthetic relationship by Andrei K. Whaley; Anastasiia O. Ponkratova; Anastasia A. Orlova; Sergey V. Volobuev; Natalia V. Shakhova; Evgeny B. Serebryakov; Sergey N. Smirnov; Natalia V. Pustovit; Liudmila A. Kraeva; Vladimir G. Luzhanin is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is New benzoquinone pigments from the hydnoid fungus Sarcodontia setosa and their biosynthetic relationship about?

Chemical investigation of the hydnoid fungus Sarcodontia setosa resulted in the isolation of five compounds, including two new sarcodontic acid derivatives -setosic acid (1) and 7,8dehydrohomosarcodontic acid (2) along with three known benzoquinone pigments -sarcodontic acid (3), 4,5-dehydrosarcodontic acid (4) and dihydrosarcodontic acid (5). The structures were elucidated using spectroscopic methods (UV, NMR and HR-ESIMS). The biosynthetic relationship of the isolated compounds is proposed and discussed. Antibacterial activity screening of compounds 1-5 against ESKAPE bacterial strains in vitro with zones of inhibition was performed and MIC values were established for the most active compounds (3 and 5).

Who reads New benzoquinone pigments from the hydnoid fungus Sarcodontia setosa and their biosynthetic relationship?

Author

Andrei K. Whaley; Anastasiia O. Ponkratova; Anastasia A. Orlova; Sergey V. Volobuev; Natalia V. Shakhova; Evgeny B. Serebryakov; Sergey N. Smirnov; Natalia V. Pustovit; Liudmila A. Kraeva; Vladimir G. Luzhanin

Publisher

Informa UK Limited

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)