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USP22 Regulates ESC Differentiation by lingzhi.liu2003 is a document available to read on EtoBox.
The study investigates the role of Ubiquitin-specific protease 22 (USP22) in embryonic stem cell (ESC) differentiation, revealing that USP22 represses the transcription of the core pluripotency factor SOX2. USP22 is induced during ESC differentiation and is necessary for the transition from self-renewal to lineage-specific differentiation. The findings highlight the epigenetic mechanisms regulating gene expression changes in ESCs, emphasizing the importance of USP22 in controlling pluripotency and different
- Author
- lingzhi.liu2003
- Language
- EN