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Can I read Base-Mediated Claisen Rearrangement of CF~3~-Containing Bisallyl Ethers on EtoBox?
Base-Mediated Claisen Rearrangement of CF~3~-Containing Bisallyl Ethers by Hamada, Yoko (author);Matsunaga, Rio (author);Kawasaki-Takasuka, Tomoko (author);Yamazaki, Takashi (author) is a Chemistry article available to read on EtoBox.
What is Base-Mediated Claisen Rearrangement of CF~3~-Containing Bisallyl Ethers about?
We have previously clarified that the strongly electron-withdrawing CF~3~ group nicely affected the base-mediated proton shift of CF~3~-containing propargylic or allylic alcohols to afford the corresponding α,β-unsaturated or saturated ketones, respectively, which was applied this time to the Claisen rearrangement after __O__-allylation of the allylic alcohols with a CF~3~ group, followed by isomerization to the corresponding allyl vinyl ethers via the proton shift, enabling the desired rearrangement in a tandem fashion, or in a stepwise manner, the latter of which was proved to have attained an excellent diastereoselectivity with the aid of a palladium catalyst.
Who reads Base-Mediated Claisen Rearrangement of CF~3~-Containing Bisallyl Ethers?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Hamada, Yoko (author);Matsunaga, Rio (author);Kawasaki-Takasuka, Tomoko (author);Yamazaki, Takashi (author)
- Publisher
- MDPI AG
- Published
- 2021
- Language
- EN
- Field
- Chemistry (Life Sciences)