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Glaucoma and neuroinflammation: An overview by Luciano Quaranta; Carlo Bruttini; Eleonora Micheletti; Anastasios G.P. Konstas; Manuele Michelessi; Francesco Oddone; Andreas Katsanos; Diego Sbardella; Giovanni De Angelis; Ivano Riva is a Medicine article available to read on EtoBox.
What is Glaucoma and neuroinflammation: An overview about?
Glaucoma is an optic neuropathy characterized by well-defined optic disc morphological changes (i.e., cup enlargement, neuroretinal border thinning, and notching, papillary vessel modifications) consequent to retinal ganglion cell loss, axonal degeneration, and lamina cribrosa remodeling. These modifications tend to be progressive and are the main cause of functional damage in glaucoma. Despite the latest findings about the pathophysiology of the disease, the exact trigger mechanisms and the mechanism of degeneration of retinal ganglion cells and their axons have not been completely elucidated. Neuroinflammation may play a role in both the development and the progression of the disease as a result of its effects on retinal environment and retinal ganglion cells. We summarize the latest findings about neuroinflammation in glaucoma and examine the connection between risk factors, neuroinflammation, and retinal ganglion cell degeneration.
Who reads Glaucoma and neuroinflammation: An overview?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Luciano Quaranta; Carlo Bruttini; Eleonora Micheletti; Anastasios G.P. Konstas; Manuele Michelessi; Francesco Oddone; Andreas Katsanos; Diego Sbardella; Giovanni De Angelis; Ivano Riva
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)