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Short TE MR Microscopy: Accurate measurement and zonal differentiation of normal hyaline cartilage by Dominique M. Freeman; Gabrielle Bergman; Gary Glover is a Medicine article available to read on EtoBox.

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## Abstract The purpose of this study was to use MR imaging to accurately measure the thickness of hyaline cartilage and determine the MR contrast parameters for differentiation of cartilage zones in normal human cartilage samples. Cartilage samples were examined using three dimensional spin‐echo MR microscopy at 9.4 T with a voxel size of 31 × 31 × 300 μm. Effects of __T__~2~ signal loss, susceptibility, and partial volume on measured thickness of cartilage were investigated. Thickness measurements were obtained on corresponding histological sections for comparison. Optimal contrast parameters for delineation of cartilage zones were evaluated using magnetization transfer, inversion recovery, __T__~1~, and __T__~2~ contrast. __T__~2~ relaxation losses were identified as the primary source of discrepancy between the measured thickness of cortical bone and hyaline cartilage. Good contrast for zonal differentiation was obtained using __T__~1~ weighting. We conclude that images obtained using short __TE__ MR microscopy can be used to accurately measure cartilage and bone thickness in human specimens, and can demonstrate zones within normal cartilage.

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Author

Dominique M. Freeman; Gabrielle Bergman; Gary Glover

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)

Published

1997

Language

EN

Field

Medicine (Health Sciences)