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What is Indirect Detection of DNA Damage Chbiol about?

This document discusses the mechanisms of nucleotide excision repair (NER) in mammalian cells, highlighting how bulky DNA lesions are detected through the recognition of unpaired bases in the undamaged complementary strand. The research by Naegeli and colleagues reveals that NER components initiate repair of nondistorting chemical lesions only when the undamaged strand is bulged due to designed base unpairing. This finding suggests a common feature shared by various DNA lesions that facilitates their detect

Author

Annisa wulan agus utami

Language

EN