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Metabolic Engineering of Pichia pastoris for Lycopene Production by yusufyekdar96 is a document available to read on EtoBox.
This research article discusses the metabolic engineering of Pichia pastoris to enhance lycopene production using a CRISPR/Cpf1-based gene repression system. The study successfully optimized gene editing and regulatory pathways, achieving a record lycopene yield of 7.24 g/L and 75.48 mg/g DCW in fed-batch fermentation. These findings provide new strategies for metabolic engineering and insights into the transcriptional regulation of metabolic pathways for carotenoid production.
- Author
- yusufyekdar96
- Language
- EN