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High-risk Pancreatic Anastomosis Versus Total Pancreatectomy After Pancreatoduodenectomy: Postoperative Outcomes and Quality of Life Analysis by Giovanni Marchegiani; Giampaolo Perri; Anna Burelli; Fabio Zoccatelli; Stefano Andrianello; Claudio Luchini; Katia Donadello; Claudio Bassi; Roberto Salvia is a Medicine article available to read on EtoBox.

What is High-risk Pancreatic Anastomosis Versus Total Pancreatectomy After Pancreatoduodenectomy: Postoperative Outcomes and Quality of Life Analysis about?

## Objective: To evaluate tp as an alternative to pd in patients at high-risk for popf. ## Background: Outcomes of high-risk pd (hr-pd) and tp have never been compared. ## Methods: All patients who underwent pd or tp between july 2017 and december 2019 were identified. hr-pd was defined according to the alternative fistula risk score. postoperative outcomes (primary endpoint), pancreatic insufficiency, and quality of life after 12 months of follow-up (qol) were compared between hr-pd or planned pd intraoperatively converted to tp (c-tp). ## Results: A total of 566 patients underwent pd and 136 underwent tp during the study period. one hundred one (18%) pd patients underwent hr-pd, whereas 86 (63%) tp patients underwent c-tp. postoperatively, the patients in the c-tp group exhibited lower rates of postpancreatectomy hemorrhage (15% vs 28%), delayed gastric emptying (16% vs 34%), sepsis (10% vs 31%), and clavien-dindo ≥3 morbidity (19% vs 31%) and had shorter median lengths of hospital stay (10 vs 21 days) (all p < 0.05). the rate of popf in the hr-pd group was 39%. mortality was comparable between the 2 groups (3% vs 4%). although general, cancer- and pancreas-specific qol were comp

Who reads High-risk Pancreatic Anastomosis Versus Total Pancreatectomy After Pancreatoduodenectomy: Postoperative Outcomes and Quality of Life Analysis?

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Author
Giovanni Marchegiani; Giampaolo Perri; Anna Burelli; Fabio Zoccatelli; Stefano Andrianello; Claudio Luchini; Katia Donadello; Claudio Bassi; Roberto Salvia
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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