Can I read Arterial hypertension and microalbuminuria in IDDM: The Italian Microalbuminuria Study on EtoBox?

Arterial hypertension and microalbuminuria in IDDM: The Italian Microalbuminuria Study by R. Mangili; G. Deferrari; U. Di Mario; O. Giampietro; R. Navalesi; R. Nosadini; G. Rigamonti; R. Spezia; G. Crepaldi; The Italian Microalbuminuria Study Group is a Medicine article available to read on EtoBox.

What is Arterial hypertension and microalbuminuria in IDDM: The Italian Microalbuminuria Study about?

Arterial hypertension and poor glycaemic control are central to the development of microalbuminuria in insulin-dependent diabetes mellitus (IDDM). Recent consensus has established sensitive criteria for their detection and treatment, although the proportion of patients who may benefit is unclear. Between 1988 and 1990, we measured urinary albumin to creatinine concentration ratio (A/C) in 3,636 adult out-patients with IDDM of more than 3 years duration, serum creatinine under 133 vmol/1 and who were not undergoing antihypertensive treatment. A/C indicating microalbuminuria (\_> 2.38/ 2.96 mg/mmol, male/female) was found in 620 of 3,451 patients without proteinuria, and associated with hypertension (blood pressure >\_ 140 and/or 90 mmHg; p = 0.0016; rate: 39.6 %), independent of diabetes duration (p =0.0082) and male gender (p = 0.0350; relative risk = 1.16; 95 % confidence interval: 1.01-1.32). Hypertension was less common among those with normal A/C (27.5 %, p \_ 2.0 mg/mmol 529 were reexamined. Glycated haemoglobin levels exceeded 3 SD above the mean of normal in 84.3 % of the 198 microalbuminuric patients (AER=20-200 ~tg/min), but were comparably poor (79.2 %) in normoalbuminur

Who reads Arterial hypertension and microalbuminuria in IDDM: The Italian Microalbuminuria Study?

Author

R. Mangili; G. Deferrari; U. Di Mario; O. Giampietro; R. Navalesi; R. Nosadini; G. Rigamonti; R. Spezia; G. Crepaldi; The Italian Microalbuminuria Study Group

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0012-186X)

Published

1994

Language

EN

Field

Medicine (Health Sciences)