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Clinical Efficacy and Safety of Certolizumab Pegol in Cutaneous Symptoms on Psoriasis in Patients with Psoriatic Arthritis : a Retrospective Analysis in Real Life by Dattola, Annunziata; Mazzeo, Mauro; Di Stefano, Flavia; Manfreda, Valeria; Vollono, Laura; Di Raimondo, Cosimo; Di Matteo, Eleonora; Bianchi, Luca is a Medicine article available to read on EtoBox.
What is Clinical Efficacy and Safety of Certolizumab Pegol in Cutaneous Symptoms on Psoriasis in Patients with Psoriatic Arthritis : a Retrospective Analysis in Real Life about?
We present the results on retrospective analysis about the efficacy of Certolizumab pegol (CZP), an antitumor necrosis factor-alpha agent, as monotherapy on skin psoriasis (PsO) in patients affect both by psoriatic arthritis (PsA) and mild-severe PsO. To date, the CZP is authorized for the treatment of PsA, PsO beyond that rheumatoid arthritis, axial spondyloarthritis/ankylosing spondylitis, and Crohn's. Assessments included an evaluation of the Psoriasis Area and Severity Index (PASI). Twelve patients (9M and 3F mean age 57.8 ± 8 years) were enrolled in our study. Nine patients had been previously treated with others biologic agents, three patients were naïve. Clinical and laboratory evaluations including PASI, erythrosedimentation rate, and C-reactive protein were performed at baseline (BL), at Week 12 (W12), Week 24 (W24), and Week 52 (W52) of treatment. Although the combination between methotrexate and CZP is allowed, we included, in our study, patients treated only with CZP. In such a way as to be as specific as possible, topical corticosteroids, vitamin D derivatives, retinoid creams, anthralin derivatives as well as p-UVA or UV-B have been forbidden to enrolled patients. Wit
Who reads Clinical Efficacy and Safety of Certolizumab Pegol in Cutaneous Symptoms on Psoriasis in Patients with Psoriatic Arthritis : a Retrospective Analysis in Real Life?
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- Author
- Dattola, Annunziata; Mazzeo, Mauro; Di Stefano, Flavia; Manfreda, Valeria; Vollono, Laura; Di Raimondo, Cosimo; Di Matteo, Eleonora; Bianchi, Luca
- Publisher
- Hindawi Limited
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)