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Numerical and in vivo validation of fast cine displacement‐encoded with stimulated echoes (DENSE) MRI for quantification of regional cardiac function by Li Feng; Robert Donnino; James Babb; Leon Axel; Daniel Kim is a Medicine article available to read on EtoBox.

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## Abstract Quantitative assessment of regional cardiac function can improve the accuracy of detecting wall motion abnormalities due to heart disease. While recently developed fast cine displacement‐encoded with stimulated echoes (DENSE) MRI is a promising modality for the quantification of regional myocardial function, it has not been validated for clinical applications. The purpose of this study, therefore, was to validate the accuracy of fast cine DENSE MRI with numerical simulation and in vivo experiments. A numerical phantom was generated to model physiologically relevant deformation of the heart, and the accuracy of fast cine DENSE was evaluated against the numerical reference. For in vivo validation, 12 controls and 13 heart‐disease patients were imaged using both fast cine DENSE and myocardial tagged MRI. Numerical simulation demonstrated that the echo‐combination DENSE reconstruction method is relatively insensitive to clinically relevant resonance frequency offsets. The strain measurements by fast cine DENSE and the numerical reference were strongly correlated and in excellent agreement (mean difference = 0.00; 95% limits of agreement were 0.01 and −0.02). The strain meas

Who reads Numerical and in vivo validation of fast cine displacement‐encoded with stimulated echoes (DENSE) MRI for quantification of regional cardiac function?

Author

Li Feng; Robert Donnino; James Babb; Leon Axel; Daniel Kim

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)

Published

2009

Language

EN

Field

Medicine (Health Sciences)