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Can I read Structural Comparison of Alkylpolyamine Analogues with Potent in Vitro Antitumor or Antiparasitic Activity on EtoBox?
Structural Comparison of Alkylpolyamine Analogues with Potent in Vitro Antitumor or Antiparasitic Activity by Frank H. Bellevue III; Michelle Boahbedason; Ronghui Wu; Patrick M. Woster; Robert A. Casero Jr.; Donna Rattendi; Schennella Lane; Cyrus J. Bacchi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Structural Comparison of Alkylpolyamine Analogues with Potent in Vitro Antitumor or Antiparasitic Activity about?
A series of symmetrically or unsymmetrically alkyl-substituted polyamine analogues were synthesized containing either a 3-3-3 or 3-7-3 polyamine backbone. These analogues were evaluated in vitro as antitumor agents in the NCI H157 and NCI H82 lung carcinoma cell lines, and as antitrypanosomal agents against four strains of Trypanosoma brucei brucei or Trypanosoma brucei rhodesiense. The resulting biological data suggest that it is possible to specifically target tumor cells or parasitic organisms with alkylpolyamine analogues based on structure.
Who reads Structural Comparison of Alkylpolyamine Analogues with Potent in Vitro Antitumor or Antiparasitic Activity?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Frank H. Bellevue III; Michelle Boahbedason; Ronghui Wu; Patrick M. Woster; Robert A. Casero Jr.; Donna Rattendi; Schennella Lane; Cyrus J. Bacchi
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 1996
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)