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Chromatin and Disease (Subcellular Biochemistry, 41) by Tapas K. Kundu (editor), Dipak Dasgupta (editor) is a nonfiction available to read on EtoBox.

What is Chromatin and Disease (Subcellular Biochemistry, 41) about?

It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics. In the light of these advances, it happens to be the right time to explore current insights into various aspect of chromatin and disease connection under one cover. Authors who are actively involved in chromatin research and have made several original contributions to develop latest paradigms in the field have writte

Who reads Chromatin and Disease (Subcellular Biochemistry, 41)?

Author

Tapas K. Kundu (editor), Dipak Dasgupta (editor)

Publisher

Springer London, Limited

Published

2007

Language

EN

ISBN

9781402054655

Category

nonfiction

Subjects

Science, Chemistry, Medical