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High Health‐related Quality of Life Among Long‐term Survivors of Childhood Acute Lymphoblastic Leukemia by Marika J. Harila; Jarmo Salo; Marjatta Lanning; Ilpo Vilkkumaa; Arja H. Harila‐Saari is a Medicine article available to read on EtoBox.
What is High Health‐related Quality of Life Among Long‐term Survivors of Childhood Acute Lymphoblastic Leukemia about?
## Abstract ## Background Health‐related quality of life (HRQoL) was assessed in a cohort of long‐term childhood acute lymphoblastic leukemia (ALL) survivors. ## Procedure Rand‐36‐Item health Survey (RAND‐36) was used to assess subjective HRQoL in 74 survivors of ALL an average of 20 years after the diagnosis. Cranial irradiation had been administered to 46 of the survivors, while 28 survivors had solely been treated with chemotherapy. The control group consisted of 146 healthy young adults selected from local population registry. Survivors were examined by a physician and late effects were graded using the Common Terminology Criteria for Adverse Events (CTCAEv3). ## Results ALL survivors achieved significantly higher scores than the controls on three of the eight HRQoL subscales; role limitations due to emotional problems (__P__ = 0.030), mental health (__P__ = 0.030) and vitality (__P__ = 0.004). In comparison to controls, survivors with a follow‐up of more than 20 years had significantly higher scores on vitality (__P__ = 0.006) and mental health (__P__ = 0.011). Survivors with severe (grade 3 and 4) late effects scored significantly better than controls on vitality (__P__ = 0.0
Who reads High Health‐related Quality of Life Among Long‐term Survivors of Childhood Acute Lymphoblastic Leukemia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Marika J. Harila; Jarmo Salo; Marjatta Lanning; Ilpo Vilkkumaa; Arja H. Harila‐Saari
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)