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Fractionated Conformal Radiotherapy in Vestibular Schwannoma: Early Results from a Single Centre by G. Horan; G.A. Whitfield; K.E. Burton; N.G. Burnet; S.J. Jefferies is a Agricultural and Biological Sciences article available to read on EtoBox.

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## Aims: To assess the local control and cranial nerve toxicity in vestibular schwannoma patients treated with fractionated conformal radiotherapy delivered using a linear accelerator. ## Materials and methods: Ninety-five patients were referred for consultation to the oncology department in addenbrookes hospital between 1996 and 2005. the 42 cases who received fractionated conformal radiotherapy are the subject of this analysis. all patients had radiological or symptomatic progression. conformal radiotherapy was prescribed at 50gy in 30 fractions over 6 weeks, delivered using a linear accelerator. patients were immobilised using either a beam direction shell or a gill thomas cosman relocatable stereotactic head frame. ## Results: The median age was 63 years (range 28-81) with 57% men. the average tumour size was 21.5mm on magnetic resonance imaging. before treatment, 20 (48%) patients were deemed to have useful hearing on the affected side. the median follow-up was 18.6 months (range 0.3-6.5 years) and the actuarial local control rate at 2.5 years was 96.9% (one patient progressed after treatment). in previously hearing patients, the actuarial rate of useful hearing preservation w

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Author

G. Horan; G.A. Whitfield; K.E. Burton; N.G. Burnet; S.J. Jefferies

Publisher

Elsevier Science; Springer; Elsevier ; Springer-Verlag; W. B. Saunders Co., Ltd.; Springer Verlag; Elsevier BV; Springer Science and Business Media LLC (ISSN 1433-2981)

Published

2007

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)