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Prospective, Longitudinal Pilot Study by Keenan, Tiarnan D.L. (author);Goldstein, Michaella (author);Goldenberg, Dafna (author);Zur, Dinah (author);Shulman, Shiri (author);Loewenstein, Anat (author) is a Medicine article available to read on EtoBox.
What is Prospective, Longitudinal Pilot Study about?
## Purpose To evaluate longitudinally the performance of the Notal Vision Home OCT (NVHO), comprising a spectral-domain OCT device for patient self-imaging at home, telemedicine infrastructure for automated data upload, and deep learning algorithm for automated OCT evaluation. The aims were to study the system’s performance in daily image acquisition and automated analysis and to characterize the dynamics of retinal fluid exudation in neovascular age-related macular degeneration (nAMD). ## Design Pilot prospective, observational longitudinal study. ## Participants Four individuals (mean age, 73.8 years) with nAMD (one or both eyes) undergoing anti–vascular endothelial growth factor therapy in routine clinical practice. ## Methods The participants performed daily self-imaging at home with the NVHO for 1 month. The macular cube scans were uploaded automatically to the Notal Health Cloud. They underwent evaluation separately by the Notal OCT Analyzer (NOA) and human expert graders for fluid presence, segmentation, and volume. ## Main Outcome Measures Daily self-imaging completion, image quality, acquisition time, agreement between automated and human grading of retinal fluid, and temp
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- Author
- Keenan, Tiarnan D.L. (author);Goldstein, Michaella (author);Goldenberg, Dafna (author);Zur, Dinah (author);Shulman, Shiri (author);Loewenstein, Anat (author)
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)