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Screening options for Down syndrome: how women choose in real clinical setting by T. K. Lo; F. K. Lai; W. C. Leung; W. L. Lau; L. S. Ng; W. C. Wong; S. S. Tam; Y. C. Yee; H. Choi; H. S. W. Lam; A. S. Y. Sham; L. C. H. Tang; R. K. H. Chin is a Medicine article available to read on EtoBox.

What is Screening options for Down syndrome: how women choose in real clinical setting about?

## Abstract ## Objective To study pregnant women's preference among various screening options for Down syndrome (DS) in routine clinical setting, and its potential association with women's demographic characteristics. ## Methods Women aged 35 years and older carrying singleton pregnancy were offered a variety of screening tests for DS before 14 weeks of gestation. Their preference was confirmed by the test they actually underwent. The association between women's choice of test and a number of demographic characteristics was studied using multinomial regression. ## Results Among 1967 eligible women, 619 opted for first‐trimester screening test (FTS), 924 for partial integrated test (PIT), and 424 for full integrated test (FIT). __Nulliparous__ women and __working__ mothers were more likely to choose FTS and FIT. Women with __history of subfertility__ were more likely to choose FIT. Women with __family history of chromosomal abnormalities__ were more likely to choose FTS. The choice of screening test could be predicted for 49.9% of women using four demographic characteristics. ## Conclusions Among older women of predominantly Chinese ethnicity, integrated test is a favorite alternati

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Author
T. K. Lo; F. K. Lai; W. C. Leung; W. L. Lau; L. S. Ng; W. C. Wong; S. S. Tam; Y. C. Yee; H. Choi; H. S. W. Lam; A. S. Y. Sham; L. C. H. Tang; R. K. H. Chin
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0197-3851)
Published
2009
Language
EN
Field
Medicine (Health Sciences)

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