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Can I read PceRBase: a database of plant competing endogenous RNA on EtoBox?
PceRBase: a database of plant competing endogenous RNA by Chunhui Yuan; Xianwen Meng; Xue Li; Nicola Illing; Robert A. Ingle; Jingjing Wang; Ming Chen is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is PceRBase: a database of plant competing endogenous RNA about?
Competition for microRNA (miRNA) binding between RNA molecules has emerged as a novel mechanism for the regulation of eukaryotic gene expression. Competing endogenous RNA (ceRNA) can act as decoys for miRNA binding, thereby forming a ceRNA network by regulating the abundance of other RNA transcripts which share the same or similar microRNA response elements. Although this type of RNA cross talk was first described in Arabidopsis, and was subsequently shown to be active in animal models, there is no database collecting potential ceRNA data for plants. We have developed a Plant ceRNA database (PceRBase, http://bis.zju.edu.cn/pcernadb/index.jsp) which contains potential ceRNA target-target, and ceRNA target-mimic pairs from 26 plant species. For example, in Arabidopsis lyrata, 311 candidate ceRNAs are identified which could affect 2646 target-miRNA-target interactions. Predicted pairing structure between miRNAs and their target mRNA transcripts, expression levels of ceRNA pairs and associated GO annotations are also stored in the database. A web interface provides convenient browsing and searching for specific genes of interest. Tools are available for the visualization and enrichment
Who reads PceRBase: a database of plant competing endogenous RNA?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Chunhui Yuan; Xianwen Meng; Xue Li; Nicola Illing; Robert A. Ingle; Jingjing Wang; Ming Chen
- Publisher
- Oxford University Press (OUP)
- Published
- 2017
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)