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Protein Containing Synthetic Surfactant Versus Animal Derived Surfactant Extract for the Prevention and Treatment of Respiratory Distress Syndrome by Robert H. Pfister; Roger Soll; Thomas E Wiswell is a book available to read on EtoBox.

What is Protein Containing Synthetic Surfactant Versus Animal Derived Surfactant Extract for the Prevention and Treatment of Respiratory Distress Syndrome about?

## Background: Respiratory distress syndrome (rds) is a significant cause of morbidity and mortality in preterm infants. rds is caused by a deficiency, dysfunction, or inactivation of pulmonary surfactant. numerous surfactants of either animal extract or synthetic design have been shown to improve outcomes. new surfactant preparations that include peptides or whole proteins that mimic endogenous surfactant protein have recently been developed and tested. ## Objectives: To assess the effect of administration of synthetic surfactant containing surfactant protein mimics compared to animal derived surfactant extract on the risk of mortality, chronic lung disease, and other morbidities associated with prematurity in preterm infants at risk for or having rds. ## Search strategy: Standard search methods of the cochrane neonatal review group were used. the search included medline (1966 - may 2007) and the cochrane central register of controlled trials (central, the cochrane library) in all languages. in addition, published abstracts of the society of pediatric research were searched electronically. for abstract books that did not include key words, the search was limited to the relevant se

Author

Robert H. Pfister; Roger Soll; Thomas E Wiswell

Publisher

John Wiley & Sons, Ltd

Published

2007

Language

EN