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SARS-COV-2-vaccine-inactivated-Sinovac-Biotech IgA vasculitis: case report A 32-year-old woman developed IgA vasculitis following vaccination with SARS-COV-2-vaccine-inactivated-Sinovac-Biotech against . The woman presented with rashes on bilateral lower extremities, the day after she received her second dose of SARS-COV-2-vaccine-inactivated-Sinovac-Biotech [CoronaVac-Sinovac] vaccine. The rashes were appeared to be initially well-defined round erythematous macules, papules and plaques, which were mostly raised. Those were associated with colicky abdominal pain and inflammatory arthritis of both knees and ankles. Her medical history was significant for allergy to seafood. The rashes later showed as well-defined erythematous round to irregularly shape on arms near the antecubital fossa, abdomen and lower extremities. On admission, skin biopsy and direct immunofluorescence showed interface dermatitis with leukocytoclastic vasculitis and IgA +1 vessel wall and fibrinogen +2 vessel wall, respectively. Investigations were consistent with IgA vasculitis, which was considered secondary to SARS-COV-2-vaccine-inactivated-Sinovac-Biotech vaccine. The woman was treated with prednisone and om

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Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)