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Initial experience with dynamic MR imaging in evaluation of normal bone marrow versus malignant bone marrow infiltrations in humans by Matthias Bollow; Wolfgang Knauf; Agnieszka Korfel; Matthias Taupitz; Andreas Schilling; Karl-Jürgen Wolf; Bernd Hamm is a Medicine article available to read on EtoBox.
What is Initial experience with dynamic MR imaging in evaluation of normal bone marrow versus malignant bone marrow infiltrations in humans about?
## Abstract The purpose of this study was (a) evaluation of dynamic contrast‐enhanced MR imaging of normal bone marrow versus malignant bone marrow infiltrations in patients with proven B‐cell‐type chronic lymphocytic leukemia (B‐CLL) and (b) correlation with the clinical stage according to Binet (stages A, B, C) and response to therapy. Bone marrow imaging of the lumbar spine, pelvis, and proximal femurs was performed at 1.5 T in 45 patients without known malignancy and in 30 patients with B‐CLL. The differences between opposed‐phase and in‐phase dynamic gradient‐echo sequences before and up to 10 minutes after intravenous application of .1 mmol/kg body weight of gadolinium‐diethylenetriamine penta‐acetic acid (Gd‐DTPA) were evaluated in normal bone marrow. The contrast‐enhancement patterns of normal and malignant bone marrow were compared using the opposed‐phase dynamic gradient‐echo sequence. Ten of the patients with bone marrow infiltrations (Binet stage C) additionally underwent MR imaging follow‐up during therapy. Opposed‐phase gradient echo sequences demonstrated a signal decrease of normal bone marrow, and in‐phase gradient echo sequences demonstrated a signal increase of n
Who reads Initial experience with dynamic MR imaging in evaluation of normal bone marrow versus malignant bone marrow infiltrations in humans?
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- Author
- Matthias Bollow; Wolfgang Knauf; Agnieszka Korfel; Matthias Taupitz; Andreas Schilling; Karl-Jürgen Wolf; Bernd Hamm
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)
- Published
- 1997
- Language
- EN
- ISBN
- 9781880070130
- Field
- Medicine (Health Sciences)