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The EGF pathway is crucial for egg-laying in C. elegans and its disruption leads to embryos hatching inside the mother, indicating a significant maternal sacrifice. In humans, mutations that keep the EGF pathway constantly active are linked to various cancers. The document discusses the roles of EGFR, NF1, and MEK in regulating cell growth and poses predictions regarding the effects of inactivating these genes.

Author

celia.ulrich

Language

EN