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Post-mortem Urinary Myoglobin Levels with Reference to the Causes of Death by Bao-Li Zhu; Kaori Ishida; Li Quan; Mari Taniguchi; Shigeki Oritani; Yasunobu Kamikodai; Masaki Q Fujita; Hitoshi Maeda is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Post-mortem Urinary Myoglobin Levels with Reference to the Causes of Death about?

To evaluate pathophysiological significance of post-mortem urinary myoglobin levels in determining the cause of death, we investigated 210 forensic autopsy cases, partially in comparison with serum levels. Post-mortem serum myoglobin levels were extraordinary high in most cases possibly due to post-mortem change. Urinary myoglobin levels did not correlate with the serum levels, showing possible post-mortem elevation in cases of a prolonged post-mortem period over 48h. A high (>1000 ng/ml), moderate (100-1000 ng/ml), slight (50-100 ng/ml) and not significant (<50 ng/ml) elevation of urinary myoglobin were observed in 26, 43, 31 and 110 cases, respectively. Half the highly elevated cases were those with a survival time over 24h. In cases of minor muscle injury such as head trauma, elevation of urinary myoglobin level was closely related to longer survival. In acute/subacute deaths with a post-mortem interval within 48h, a significant difference was observed in relation to the blood carboxyhemoglobin (COHb) levels of fire victims: myoglobinuria over 100 ng/ml was more frequently and markedly observed in cases with COHb below 60% than over 60%, suggesting muscle damage in fatal burns.

Who reads Post-mortem Urinary Myoglobin Levels with Reference to the Causes of Death?

Author

Bao-Li Zhu; Kaori Ishida; Li Quan; Mari Taniguchi; Shigeki Oritani; Yasunobu Kamikodai; Masaki Q Fujita; Hitoshi Maeda

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0379-0738)

Published

2001

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)