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Can I read Effects of Isosteric Pyridone Replacements in Androgen Receptor Antagonists Based on 1,2-Dihydro- and 1,2,3,4-Tetrahydro-2,2-dimethyl-6-trifluoromethyl-8-pyridono[5,6-g]quinolines on EtoBox?

Effects of Isosteric Pyridone Replacements in Androgen Receptor Antagonists Based on 1,2-Dihydro- and 1,2,3,4-Tetrahydro-2,2-dimethyl-6-trifluoromethyl-8-pyridono[5,6-g]quinolines by James W Kong; Lawrence G Hamann; Daniel A Ruppar; James P Edwards; Keith B Marschke; Todd K Jones is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Effects of Isosteric Pyridone Replacements in Androgen Receptor Antagonists Based on 1,2-Dihydro- and 1,2,3,4-Tetrahydro-2,2-dimethyl-6-trifluoromethyl-8-pyridono[5,6-g]quinolines about?

AbstractÐA series of nonsteroidal human androgen receptor (hAR) antagonists based on 8-substituted 1,2-dihydro-and 1,2,3,4tetrahydro-2,2-dimethyl-6-tri ̄uoromethylpyrido[3,2-g]quinolines was synthesized. Compounds in this series were tested for the ability to bind to hAR and inhibit hAR-dependent transcription in a mammalian cellular background.

Who reads Effects of Isosteric Pyridone Replacements in Androgen Receptor Antagonists Based on 1,2-Dihydro- and 1,2,3,4-Tetrahydro-2,2-dimethyl-6-trifluoromethyl-8-pyridono[5,6-g]quinolines?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
James W Kong; Lawrence G Hamann; Daniel A Ruppar; James P Edwards; Keith B Marschke; Todd K Jones
Publisher
Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
Published
2000
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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