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Can I read 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study on EtoBox?
18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study by Emmanuel Ledoult; Maxime Morelle; Michael Soussan; Arsène Mékinian; Hélène Béhal; Vincent Sobanski; Eric Hachulla; Damien Huglo; Noémie Le Gouellec; Martine Remy-Jardin; Clio Baillet; David Launay is a Medicine article available to read on EtoBox.
What is 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study about?
## Abstract ## Background Interstitial lung disease is a common complication of systemic sclerosis (SSc-ILD), and it remains difficult to accurately predict its course. Progressing ILD could be more metabolically active, suggesting that the ^18^F-FDG tracer could be a tool in the managing of SSc-ILD. ## Methods In our center, SSc patients and controls (non-Hodgkin lymphoma cured after first-line regimen) who had received a PET/CT were screened retrospectively. The FDG uptake (visual intensity, pattern, SUV~max~) was systematically recorded in > 30 regions of interest (ROIs) linked to SSc in a blind reviewing by 2 independent nuclear medicine physicians using a standardized form. ## Results Among the 545 SSc patients followed up in our center, 36, including 22 SSc-ILDs, had a PET/CT, whose indication was cancer screening in most cases. The mean ± SD age was 57.9 ± 13.0 years with 20/36 females. Fourteen patients had a disease duration of less than 2 years. A third had anti-centromere antibodies and 27.8% had anti-topoisomerase antibodies. Pulmonary FDG uptakes were higher in SSc patients than in controls (n = 89), especially in those with ILD compared with those without ILD. Pulmona
Who reads 18F-FDG positron emission tomography scanning in systemic sclerosis-associated interstitial lung disease: a pilot study?
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- Author
- Emmanuel Ledoult; Maxime Morelle; Michael Soussan; Arsène Mékinian; Hélène Béhal; Vincent Sobanski; Eric Hachulla; Damien Huglo; Noémie Le Gouellec; Martine Remy-Jardin; Clio Baillet; David Launay
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)