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This systematic review and meta-analysis evaluates the diagnostic accuracy of physical examination (PE) and pulse oximetry (PO) for screening critical congenital heart disease (CCHD) in newborns. The study analyzed 20 articles involving 872,549 screened newborns, finding that the combined screening method of PE and PO significantly improves sensitivity and specificity compared to either method alone. The authors recommend implementing both methods, especially in low-resource settings where prenatal ultrasou

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iovde936

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EN