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1. Fibrous dysplasia is caused by a postzygotic mutation in the GNAS1 gene leading to continuous activation of G-proteins and cAMP production, affecting bone and tooth development. It can be monostotic, craniofacial, or polystotic. Radiographically, it appears ground-glass or orange-peel like. Histologically, bone trabeculae are arranged in a Chinese-pattern without osteoblastic rimming. 2. Paget

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