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Human Dopamine Transporter Structures by youssef.1423064 is a document available to read on EtoBox.
This article presents the structural analysis of the human dopamine transporter (hDAT) in various states, revealing its crucial role in dopamine reuptake and implications for drug interactions. The study identifies distinct binding modes for dopamine and several inhibitors, providing insights into the mechanisms of psychostimulant drugs and potential therapeutic strategies for cocaine addiction and ADHD. These findings establish a foundational understanding of hDAT
- Author
- youssef.1423064
- Language
- EN