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Antimicrobial Agents and Chemotherapy 2020 Lubis E02539 19full by boganfri is a document available to read on EtoBox.
This study investigates the genetic loci pfcrt, pfmdr1, and pfk13 in Plasmodium falciparum isolates from Northwestern Indonesia to assess the impact of artemisinin-based combination therapy (ACT) on malaria treatment efficacy. The pfcrt haplotype SVMNT was found to be the most prevalent, with only a small percentage of isolates showing mutations in pfk13 associated with artemisinin resistance. While current ACT regimens remain effective, the presence of submicroscopic infections indicates a need for ongoing
- Author
- boganfri
- Language
- EN