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Telomerases : Chemistry, Biology, and Clinical Applications by Lue, Neal F. (editor);Autexier, Chantal (editor) is a nonfiction available to read on EtoBox.

What is Telomerases : Chemistry, Biology, and Clinical Applications about?

This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed. Content: Chapter 1 The Telomerase Complex: An Overview (pages 1–21): Johanna Mancini and Chantal Autexier Chapter 2 Telomerase RNA: Structure, Function, and Molecular Mechanisms (pages 23–51): Yehuda Tzfati and Julian J.?L. Chen Chapter 3 TERT Structure, Function, and Molecular Mechanisms (pages 53–78): Emmanuel Skordalakes and Neal F. Lue Chapter 4 Telomerase Biogenesis: RNA Processing, Trafficking, and Protein Interactions (pages 79–103): Tara Beattie and Pascal Chartrand Chapter 5 Transcriptional Regulation of Human Telomerase (pages 105–134): Antonella Fars

Who reads Telomerases : Chemistry, Biology, and Clinical Applications?

Author

Lue, Neal F. (editor);Autexier, Chantal (editor)

Publisher

John Wiley & Sons, Incorporated

Published

2012

Language

EN

ISBN

9781118267516

Category

nonfiction

Subjects

Science, Chemistry, Medical